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In turn, in GBM, GPX4 and LRP8 play a role in survivial [72, 75]

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So, it is very important to define the vulnerability of the different neuronal populations in terms of susceptibility to oxidative stress in physiological conditions in order to extent this knowledge to improve our understanding of how this particular form of cell vulnerability causes selective neuronal losses in nervous system, as well as reveal potential molecular and cellular mechanisms that bring about relative resistance or sensitivity of neurons to stresses